Upon their arrival, the Mexican immigrants faced yet another hardship. Discrimination. Mexican children were not allowed into certain schools, while their parents were not allowed to shop in many places. The Mexicans were also exploited in the workplace and basic services offered by area hospitals and government agencies were not granted to the Mexicans. Not knowing where to turn or how to respond, the need for basic services within the Mexican community continued to grow.
To answer this growing need, a Catholic women's club in 1919 decided to establish a volunteer school and clinic for the underprivileged Mexican immigrants who had settled in the Westside. Naming the entity after the patron saint of Mexico, the Guadalupe Center became one of the nation's first social service agencies for Latinos and has grown to be the heart of the Latino community within Kansas City.